The Old Gotham Freeway was a stretch of road that encompassed Park Row and Amusement Mile. When Arkham City was constructed, the freeway was incorporated into it. After Protocol 10, part of it was destroyed.
Arkham City Incident
In addition to that, the freeway was destroyed by the Penguin to prevent the Joker from sending his henchmen into his territory. Vicki Vale was stranded and targeted by snipers on that freeway when her helicopter was shot down by the Joker.
After Arkham City Incident
The Freeway was reconstructed after Arkham City was closed down.