The Department of Extranormal Operations (DEO) is a United States Government Agency that was tasked with closely monitoring and if necessary interfering with known metahumans.
Arkham Origins Blackgate Incident
Three months after the events at Blackgate, Catwoman infiltrated and stole classified data from one of the DEO's buildings. As a result, the DEO proceeded to send a squad to hunt her down shortly after Batman interfered. Even though Batman was trying to stop Catwoman, the DEO also targeted Batman due to mistakingly assuming that he was an accomplice in her theft, thus forcing the Dark Knight to neutralize all the DEO soldiers in his path while simultaneously pursuing Catwoman.
- Amanda Waller in the comics was a member of the DEO, although in the Arkham series, she's a member of the Department of Justice instead.